Alternative strategy for covid-19 treatment

According to the latest Establishment scientific evidence below, coronavirus will be with us for the rest of my life. As I am technically “clinically vulnerable” (over 70, co-mobidities, annual flu jab etc), I thought that in the event of contracting covid-19, I would look at alternative treatment strategies to the government recommended self isolation strategy.

Coronavirus testing

The UK will be living with coronavirus for many years to come and even a vaccine is unlikely to eliminate it for good, experts are warning. Wellcome Trust director Prof Sir Jeremy Farrar told the House of Commons’ Health Committee “things will not be done by Christmas”. This infection is not going away, it’s now a human endemic infection. “Even, actually, if we have a vaccine or very good treatments, humanity will still be living with this virus for very many, many years…. decades to come.”

Prof Sir John Bell, of the University of Oxford, said he thought it was unlikely that Covid-19 would ever be eliminated despite the positive news announced on Monday that trials by his university had triggered an immune response – an important step in developing a vaccine. “The reality is that this pathogen is here forever, it isn’t going anywhere,” he told MPs. Click here for full BBC article.

Government guidance Click here for full Government guidance.

If you have symptoms of COVID-19, however mild, OR you have received a positive COVID-19 test result, the clear medical advice is to immediately self-isolate at home for at least 7 days from when your symptoms started. Do not go to a GP surgery, pharmacy or hospital. You should arrange to have a test to see if you have COVID-19 – go to testing to arrange. After 7 days, or longer, if you still have symptoms other than cough or loss of sense of smell/taste, you must continue to self-isolate until you feel better.

Where possible, arrange for anyone who is clinically vulnerable or clinically extremely vulnerable to move out of your home, to stay with friends or family for the duration of your home isolation period. If you cannot arrange for vulnerable people to move out of your home, stay away from them as much as possible, following the guidance here. For the clinically extremely vulnerable please follow the Shielding guidance.

Arguably, this is the worst possible approach for the clinically vulnerable or clinically extremely vulnerable if they start to display covid-19 symptoms, as they isolate infected high-risk people until they develop serious respiratory problems and need hospital treatment.

Alternative strategy

The lethality of Covid-19 is much lower than initially assumed – most people develop mild symptoms at most – but people at high risk or high exposure need early or prophylactic treatment.

Leading doctors from the US, Europe and Asia have reported striking success with early interventions based on zinc-chloroquine and zinc-quercetin combination protocols, including dramatic reductions in hospitalization and mortality rates and improvements in the condition of patients within hours.

The effectiveness of chloroquine against coronaviruses was discovered already back in 2005 in the wake of SARS-1. The fact that zinc blocks coronavirus RNA replication was discovered in 2010 by world-leading SARS virologist Ralph Baric. The fact that chloroquine and quercetin support cellular zinc uptake was discovered in 2014 in the context of cancer and virology research.

The alleged or actual negative results with chloroquine in some studies were based on delayed use (intensive care patients), excessive doses (up to 2400mg per day), manipulated data sets (the Surgisphere scandal), or ignored contraindications (e.g., favism or heart problems).

Based on the available scientific evidence and current clinical experience, the Swiss Policy Research Collaboration recommends that physicians and authorities consider the following Covid-19 treatment protocol for the early treatment of people at high risk or high exposure.

Based on this and very similar protocols, US physicians reported an 84% decrease in hospitalization rates, a 50% decrease in mortality rates among already hospitalized patients (if treated early), and an improvement in the condition of patients often within hours.

Treatment protocol

  1. Zinc (75mg to 100mg per day)
  2. Hydroxychloroquine (400mg per day)
  3. Quercetin (500mg to 1000mg per day)
  4. Azithromycin (up to 500mg per day)
  5. Heparin (usual dosage)

The primary component is zinc, which inhibits RNA polymerase activity of coronaviruses and thus blocks virus replication (see references below). Hydroxychloroquine and quercetin support the cellular absorption of zinc. Azithromycin prevents bacterial superinfections. Heparin prevents infection-related thromboses and embolisms in patients at risk.

Note: Quercetin may be used in addition to or as a replacement of HCQ. Contraindications for HCQ (e.g. favism or heart problems) and azithromycin must be observed.

Click for full SPR articles

Update 4th August

Revised Treatment protocol

  1. Zinc (50mg to 100mg per day)º
  2. Hydroxychloroquine (400mg per day)*º
  3. Quercetin (500mg to 1000mg per day)º
  4. Bromhexine (50mg to 100mg per day)º
  5. Azithromycin (up to 500mg per day)*
  6. Heparin (usual dosage)*

*) Prescription only (in most countries)
º) Also prophylactically (for high-risk persons)

Additional notes

The early treatment of patients as soon as the first typical symptoms appear and even without a PCR test is essential to prevent progression of the disease. Zinc, HCQ, quercetin and bromhexin may also be used prophylactically for people at high risk or high exposure (e.g. for health care workers).

In contrast, isolating infected high-risk patients at home and without early treatment until they develop serious respiratory problems, as often happened during lockdowns, may be detrimental. Early treatment based on the above protocol is intended to avoid hospitalization. It is conceivable that the above treatment protocol, which is simple, safe and inexpensive, could render more complex medications, vaccinations, and other measures largely obsolete.

I did write to my GP about all this – “Good evening, could you please pass this on to my GP – not sure with whom I’m registered with. As SAGE scientists are now saying coronavirus will become endemic, and will be with us forever, and as I am technically clinically vulnerable, I have been looking at alternative treatment strategies for covid-19, in the event of contracting the virus. 

I am not particularly worried, but I would like to have a fighting chance of surviving covid-19 if I contracted it. It strikes me that if I get symptoms, follow Government policy and get tested and self – isolate for 7-14 days, and wait for serious symptoms to develop and then get hospitalised, there is a high probability of a poor clinical outcome with palliative care only by that stage.

I wondered if you know of any UK trials of this new prophylactic treatment  protocol ,and how one would go about being recruited to such a trial in the event of contracting covid-19 symptoms ? One would need the treatment protocol to start within the first few days of the onset of symptoms, so would need us (Surgery, You and me) to be registered, signed up and ready to go immediately. Pretty sure this is NOT fake. I am assuming that you would not be able to initiate such a prophylactic treatment protocol off your own bat if I requested it ?”

Needless to say, this is not possible. I have decided to buy the zinc, quercetin and bromhexine in the suggested doses, which are widely available online or from health stores as health supplements. In the event of covid-19 symptoms, I will start these immediately as a prophylactic treatment rather than sit at home and wait for symptoms to progress ………….

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